On Sunday afternoon, the Jacksonville Jaguars will seek to continue their five-game winning streak when they host the San Francisco 49ers. Jacksonville (6-2) was idle in Week 9 but defeated Pittsburgh 20-10 in Week 8. San Francisco (5-3) had dropped three straight games before the bye week, most recently 31-17 at home to Cincinnati. The teams last met in 2021, with San Francisco winning 30-10. In 2023, the Jaguars are 6-2 against the spread, while the 49ers are 4-4 ATS.
The game will begin at 1 p.m. ET from EverBank Stadium. According to SportsLine consensus, the 49ers are a 3-point favorite over the Jaguars, with the over/under set at 45. Before making your own Jaguars vs. 49ers predictions, check out SportsLine’s NFL predictions and betting recommendations from the computer simulation model.
Since its inception, the program, which simulates every NFL game 10,000 times, has returned well over $7,000 for $100 players on top-rated NFL picks. The model enters Week 10 of the 2023 NFL season with a 174-123 record on top-rated NFL picks dating back to the 2017 season. Since Week 7 of last season, it has gone 28-15 on top-rated NFL picks.
The model also rated in the top 10 on NFLPickWatch for straight-up NFL picks four times in the last six years and beat more than 94% of CBS Sports Football Pick’em players four times during that time. Anyone who has followed it is on the right track.
The model has now locked in its picks and NFL Week 10 predictions for the 49ers vs. Jaguars.You can now view the model’s picks on SportsLine. Here are some NFL odds and betting lines for the Jaguars vs. 49ers game:
Jaguars vs. 49ers spread: 49ers -3
Jaguars vs. 49ers over/under: 45 points
Jaguars vs. 49ers money line: 49ers -170, Jaguars +143
Jaguars vs. 49ers picks: See picks at SportsLine
Jaguars vs. 49ers live stream: fubo (try for free)
Why the 49ers can coverSan Francisco has scored 17 points in each of its last three games, despite winning four of their first five games by double digits. QB Brock Purdy tossed nine touchdown passes and zero interceptions in the 49ers’ five triumphs. He has thrown five interceptions against three touchdowns in his last three losses. Purdy must play practically turnover-free football for San Francisco to overcome its issues, especially against a tough opponent in Jacksonville.
The influence of running back Christian McCaffrey, who has now carried for nine touchdowns and caught four, is what makes the San Francisco system work so efficiently. McCaffrey has scored at least one touchdown in 17 straight games since joining the 49ers in the middle of the 2022 season, and he remains the league’s most explosive rushing/receiving threat out of the backfield. After gaining at least 85 yards in each of the first four games of the season, he hasn’t gained more than 55 yards since. A strong performance from San Francisco’s finest player might help them win and cover this tiny spread.Check out which team to select here.
Why the Jaguars can cover
Travis Etienne is doing his best McCaffrey impersonation, scoring seven touchdowns in his last four games and becoming a dynamic danger both on the ground and through the air. Etienne has run for 583 yards and grabbed 27 catches for 266 yards this season, scoring eight times. Despite only having one 100-yard rushing performance this season, Etienne has reached the 50-yard mark in seven of eight games.
Trevor Lawrence, the team’s quarterback, has passed for 1,935 yards with a 68.3 percent completion rate. He’s thrown nine touchdowns and four interceptions while working with a slew of weaponry that includes Etienne, wide receivers Calvin Ridley and Christian Kirk, and tight end Evan Engram. Lawrence must use his offensive arsenal to move the ball more freely against a stout San Francisco defense.Check out which team to select here.
How to make 49ers vs. Jaguars picks
The model has run 10,000 simulations of San Francisco vs. Jacksonville, and the results are in. The point total is leaning Under, and one side of the spread is the superior value.Only at SportsLine can you view the model’s Jaguars vs. 49ers pick.
So, who will win the game between Jacksonville and San Francisco on Sunday, and which side of the spread offers the best value?Visit SportsLine right now to find out which side of the 49ers vs. Jaguars spread you should bet on on Sunday, based on the model’s 174-123 record on its top-rated NFL picks.
