First, the Lions have an excellent offensive line, which gives them a chance against the 49ers. The Minnesota Vikings have a good offensive line that allowed Kirk Cousins ​​to wear down the 49ers defense.
The Lions offensive line can do the same for Jared Goff, who is immobile and uncomfortable with the bodies around him, but has a phenomenal arm and is mentally strong. 
The 49ers invested a lot of money in their defensive line, which didn’t work against the Packers.
If things don’t work out against the Lions, the 49ers will be in trouble.
Detroit running back Jahmyr Gibbs is one of the most explosive running backs in the NFL – the 49ers will have a hard time stopping him from running around the perimeter because they don’t establish good edges in the running game .
